The Bayesian kitchen

Statistical inference and evolutionary biology

Thursday, December 15, 2016

Site-specific selection and evolutionary distances

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Coming back the Microsporidia example, the LG model does not just give an artifactual position for Microsporidia. It also gives an estimate...
Tuesday, December 13, 2016

Second-order amino-acid replacement processes

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As I mentioned earlier, classical amino-acid replacement matrices indirectly encode site-specific amino-acid preferences in their first-ord...
3 comments:
Wednesday, December 7, 2016

The effective number of amino-acids per site

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As we have seen, a fundamental consequence of site-specific selective constraints is that the number of amino-acids allowed at each site is...
2 comments:
Tuesday, November 29, 2016

Site-specific selection and phylogenetic accuracy

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In my last post , I argued that classical amino-acid replacement matrices do not faithfully describe the long-term evolutionary process at...
Friday, November 25, 2016

Double standard (2)

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Just a side remark: in my last post, I pointed out that classical amino-acid replacement matrices implicitly encode site-specific selection...
Wednesday, November 23, 2016

Long-term site-specific selective constraints

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There is a catch in my argument about the  double standards   of some of the current phylogenetic models, concerning rate- versus pattern-h...
Tuesday, November 22, 2016

Double standard

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Nobody today would publish a phylogeny that has been inferred using a model that does not account for rate variation across sites, at least...
2 comments:
Monday, November 21, 2016

Ctenophores and the role of models in phylogenetics

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I gave a phyloseminar last week, on the problem of dealing with patter-heterogeneity across sites in phylogenetic inference. I find this i...

Resurrection

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This blog has been silent for such a long time (two years…). But there are quite a few things I would like to share with you, concerning ...
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